Karolina Sulek

Post-doctoral Fellow

Liggins Institute & School of Biological Sciences, University of Auckland

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RESEARCH INTERESTS

  • Analytical chemistry
  • LCMS and GCMS based metabolomics
  • Human and animal metabolic abnormalities
  • Biomarkers discovery
  • Multivariate analysis
  • Statistics

 

BACKGROUND

  • 2009-2012 - PhD, Technical University of Denmark, Denmark
    • Title of the project: Bacterial Impact on the Gut Metabolome
  • 2011 External research, Metabolomics Applied to Industrial and Medical Microbiology
  • University of Auckland, New Zealand
    • Focus on: Metabolite extraction from animal samples
    • Additional work: Secondary fungal metabolites
  • 2003-2008 - Master of Science in Engineering, Warsaw University of Technology, Poland
    • Specialization: Biotechnology
  • 2007-2008 - Aalborg University (Socrates-Erasmus Student Mobility Program), Denmark
    • Student project: Ammonia removal by bio-filtration

 

CURRENT RESEARCH

I work in a collaborative project between Prof. Phillip Baker (Liggins Institute) and Villas-Boas lab. Our aim is to develop screening tests for major pregnancy complications: preeclampsia, preterm birth and fetal growth restriction. These complications are responsible for massive maternal and fetal complications, and surviving babies are at increased risk of serious diseases in adulthood: such as heart disease, hypertension and diabetes. In addition, we are interested in developing methods to study environmental exposures in pregnancy, and to study whether effects of treatments in pregnancy lead to changes in the metabolomic profile which suggest likely efficacy. My position of post-doctoral fellow at the University of Auckland involves development of mass spectrometry methods for metabolite profiling of biological fluids: serum, plasma and urine.

 

 

SELECTED PUBLICATIONS

  • Sulek, K.; Frandsen, H.L.; Smedsgaard, J.; Skov, T.H.; Wilcks, A.; Licht, T.R. (2012); Metabolic footprint of Lactobacillus acidophilus NCFM at different pH; Metabolomics, 8, 2:244-252; DOI: 10.1007/s11306-011-0305-4
  • Vigsnaes, L.K. and van den Abbeele, P.; Sulek, K.; Frandsen, H.L.; Steenholdt, C.; Brynskov, J.; van de Wiele, T.; Licht, T.R. (2013); Microbiotas from UC patients display altered metabolism and a reduced ability of LAB to colonize mucus; Sci Rep., 3:1110; DOI: 10.1038/srep01110. Epub 2013 Jan 23

 

LINKS

http://www.gravida.org.nz/

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